Gene-Environment Interplay in the Generation of Health and Education Inequalities


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Project Details

GEIGHEI examines how Genes and the Environment (GxE) interact to generate inequalities in education and health over the life course. We test two novel hypotheses:

  1. Children born into advantaged environments are better able to reach their genetically conditioned education potential;
  2. A privileged environment protects against genetic susceptibility to risky health behaviour.

Both hypotheses propose a GxE interplay that influences the transition from early childhood to adulthood in periods that are critical to the generation of inequalities.

Project Website

Principal Investigators

Recent Publications

Stop Meta-Analyzing, Start Instrumenting: Maximizing the Predictive Power of Polygenic Scores

Titus J. Galama, Pietro Biroli, S. Fleur W. Meddens, Stephanie von Hinke, Dilnoza Muslimova, Hans van Kippersluis, Cornelius Rietveld, Rita Pereira |

Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction

Perline A. Demange, Margherita Malanchini, Travis T. Mallard, Pietro Biroli, Simon R. Cox, Andrew D. Grotzinger, Elliot M. Tucker-Drob, Abdel Abdellaoui, Louise Arseneault, Elsje van Bergen, Dorret I. Boomsma, Avshalom Caspi, David L. Corcoran, Benjamin W. Domingue, Kathleen Mullan Harris, Hill F. Ip, Colter Mitchell, Terrie E. Moffitt, Richie Poulton, Joseph A. Prinz, Karen Sugden, Jasmin Wertz, Benjamin S. Williams, Eveline L. de Zeeuw, Daniel W. Belsky, K. Paige Harden, Michel G. Nivard |

Dynamic complementarity in skill production: Evidence from genetic endowments and birth order

Dilnoza Muslimova, Hans van Kippersluis, Cornelius Rietveld, Stephanie von Hinke, S. Fleur W. Meddens |

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Research Themes


General public: Our key intended audience is the general public, and our key message is that behaviour is not deterministically driven by genes (no genetic determinism) nor environments (no environmental determinism).