Pre- and perinatal influences

Associations Between Maternal Antenatal Corticosteroid Treatment and Mental and Behavioural Disorders in Children

Babies whose mothers are treated with steroid drugs during pregnancy are significantly more likely to suffer from later mental and behavioural disorders, this research finds. The study looks at data on 670,000 children born in Finland between 2006 and 2017 and assesses whether the drugs – commonly administered to help a foetus mature when premature … Read more

Subjective Well-Being and Self-Esteem in Preterm Born Adolescents: An Individual Participant Data Meta-Analysis

This paper looks at the self-reported well-being and self-esteem of adolescents born very preterm and moderate to late preterm compared with those born full-term. Using information on around 14,500 people born In the UK, Germany and Switzerland, and whose lives were tracked into adolescence, the researchers found no difference between the general well-being around family, … Read more

Mental health outcomes of adults born very preterm or with very low birth weight: A systematic review

Preterm birth research is poised to explore the mental health of adults born very preterm(VP;<32+0 weeks gestational age) and/or very low birth weight(VLBW;<1500g) through individual participant data meta-analyses, but first the previous evidence needs to be understood. We systematically reviewed and assessed the quality of the evidence from VP/VLBW studies with mental health symptoms or … Read more

Common Core Assessments in follow-up studies of adults born preterm – Recommendation of the Adults Born Preterm International Collaboration

Background: Of all newborns, 1%-2% are born very preterm (VP; <32 weeks) or with very low birthweight (VLBW; ≤1500 g). Advances in prenatal and neonatal care have substantially improved their survival, and the first generations who have benefited from these advances are now entering middle age. While most lead healthy lives, on average these adults … Read more

Physical Activity, Mental Health, and Well‐Being in Very Pre‐Term and Term Born Adolescents: An Individual Participant Data Meta‐Analysis of Two Accelerometry Studies

This study looks at whether physical activity is associated with better mental health and well‐being among very preterm (≤32 weeks) and term born (≥37 weeks) adolescents alike or whether the associations are stronger in either of the groups. It finds that those young people in the study who exercised more had fewer problems with their … Read more

The Interplay between Maternal Smoking and Genes in Offspring Birth Weight

This paper looks at the relationships between genes, smoking, and birth weight. It finds that each additional daily cigarette smoked during pregnancy reduces birthweight by between 20 and 40 grams, regardless of the childs’s genetic predisposition. The researchers used information from a sample of 5000 mother-baby pairs in the Avon Longitudinal Study of Parents and … Read more

Association of Preterm Birth and Low Birth Weight With Romantic Partnership, Sexual Intercourse, and Parenthood in Adulthood: A Systematic Review and Meta-analysis

This systematic review and analysis of existing research suggests that adults born preterm or with low birth weight are less likely than adults born full-term to experience a romantic partnership, sexual intercourse, or to become parents. However, preterm birth or low birth weight does not seem to impair the quality of relationships with partners and … Read more

Is Social Inequality in Cognitive Outcomes Increased by Preterm Birth–Related Complications?

Dieter Wolke writes in an editorial about the relationship between maternal socioeconomic status and children’s cognitive outcomes among preterm children. He re-emphasizes what was emphasized already 40 years ago – the need to study the effect of family, social, and caretaking as risk factors in developmental outcomes among children born at high neonatal risk.

Fetal programming of neuropsychiatric disorders by maternal pregnancy depression: a systematic mini review